Article

Compliance with Ambulatory Saliva Sampling in the Chicago Health, Aging, and Social Relations Study and Associations with Social Support

Author(s) / Creator(s)

Kudielka, Brigitte M.
Hawkley, Louise C.
Adam, Emma K.
Cacioppo, John T.

Abstract / Description

Background: Noncompliance with instructed saliva sampling times in ambulatory settings can compromise resulting cortisol findings. Purpose and Methods: Here, the impact of noncompliance on the cortisol awakening response (CAR), an established marker for hypothalamic-pituitary-adrenal axis activity, was examined over 3 sampling days in middle- and older-age participants in the Chicago Health, Aging, and Social Relations Study. Results: Noncompliant participants had a significantly lower cortisol rise after awakening (assessed by an awakening sample and a 30-min after awakening sample) on 2 of the 3 sampling days (Day 1, ns; Days 2 & 3, ps < .02). Furthermore, social support measured by the Interpersonal Support Evaluation List correlated negatively with the number of "noncompliant" samples (r = -.19, p < .05), indicating that participants reporting more social support had more 'compliant' samples. Conclusion: The results confirm that nonadherence to saliva sampling in ambulatory settings can exert a significant impact on the resulting CAR. Furthermore, the data raise the idea that the extent of nonadherence might be systematically associated with psychosocial factors like social support. For future studies on the relationship between CAR and psychological factors, we therefore recommend controlling for saliva sampling adherence because noncompliance might be systematically associated with the phenomenon being investigated.

Keyword(s)

Studie Komplianz soziale Unterstützung cortisol awakening response compliance social support

Persistent Identifier

Date of first publication

2007

Publication status

unknown

Review status

unknown

Citation

  • Author(s) / Creator(s)
    Kudielka, Brigitte M.
  • Author(s) / Creator(s)
    Hawkley, Louise C.
  • Author(s) / Creator(s)
    Adam, Emma K.
  • Author(s) / Creator(s)
    Cacioppo, John T.
  • PsychArchives acquisition timestamp
    2022-11-22T06:49:46Z
  • Made available on
    2008-05-15
  • Made available on
    2015-12-01T10:30:34Z
  • Made available on
    2022-11-22T06:49:46Z
  • Date of first publication
    2007
  • Abstract / Description
    Background: Noncompliance with instructed saliva sampling times in ambulatory settings can compromise resulting cortisol findings. Purpose and Methods: Here, the impact of noncompliance on the cortisol awakening response (CAR), an established marker for hypothalamic-pituitary-adrenal axis activity, was examined over 3 sampling days in middle- and older-age participants in the Chicago Health, Aging, and Social Relations Study. Results: Noncompliant participants had a significantly lower cortisol rise after awakening (assessed by an awakening sample and a 30-min after awakening sample) on 2 of the 3 sampling days (Day 1, ns; Days 2 & 3, ps < .02). Furthermore, social support measured by the Interpersonal Support Evaluation List correlated negatively with the number of "noncompliant" samples (r = -.19, p < .05), indicating that participants reporting more social support had more 'compliant' samples. Conclusion: The results confirm that nonadherence to saliva sampling in ambulatory settings can exert a significant impact on the resulting CAR. Furthermore, the data raise the idea that the extent of nonadherence might be systematically associated with psychosocial factors like social support. For future studies on the relationship between CAR and psychological factors, we therefore recommend controlling for saliva sampling adherence because noncompliance might be systematically associated with the phenomenon being investigated.
    en
  • Publication status
    unknown
  • Review status
    unknown
  • ISSN
    0883-6612
  • Persistent Identifier
    https://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bsz:291-psydok-15851
  • Persistent Identifier
    https://hdl.handle.net/20.500.11780/470
  • Persistent Identifier
    https://doi.org/10.23668/psycharchives.11286
  • Language of content
    eng
  • Is part of
    Annals of Behavioral Medicine, 34:209-216.
  • Keyword(s)
    Studie
    de
  • Keyword(s)
    Komplianz
    de
  • Keyword(s)
    soziale Unterstützung
    de
  • Keyword(s)
    cortisol awakening response
    en
  • Keyword(s)
    compliance
    en
  • Keyword(s)
    social support
    en
  • Dewey Decimal Classification number(s)
    150
  • Title
    Compliance with Ambulatory Saliva Sampling in the Chicago Health, Aging, and Social Relations Study and Associations with Social Support
    en
  • DRO type
    article
  • Visible tag(s)
    PsyDok